Cut the chicken breasts into bite-sized pieces.
Set aside.
In a medium bowl, mix the flour, salt, black pepper, and garlic powder.
In another bowl, pour the buttermilk.
Dip each chicken piece into the buttermilk, then coat with the flour mixture.
Set the coated pieces on a plate.
Preheat your air fryer to 400°F.
Arrange the chicken pieces in a single layer in the air fryer basket and spray lightly with cooking spray.
Cook for 8-10 minutes, shaking halfway through for even cooking.
Ensure the internal temperature reaches 165°F.
Toss the cooked chicken pieces in buffalo sauce until evenly coated.
Serve immediately with your favorite dipping sauces.