Combine the buttermilk and hot sauce in a large bowl.
Soak the alligator meat in this mixture for at least two hours to let the flavors infuse.
In a separate shallow dish, mix the flour, bread crumbs, Cajun seasoning, salt, and black pepper.
This forms your dredging mixture.
Remove the marinated alligator meat and coat it thoroughly with the flour mixture.
Make sure every piece is evenly covered.
Heat the oil in a large pot or deep fryer to approximately 350°F.
Carefully place the coated alligator into the hot oil.
Fry until golden brown and crispy.
Remove the fried alligator from the oil and drain on paper towels to remove excess oil.