Cover chicken breasts with plastic wrap and pound lightly with a meat mallet.
Mix flour, garlic powder, onion powder, paprika, salt, and pepper in a plastic bag.
Add chicken breasts to the bag one at a time and coat evenly with the flour mixture.
Place coated chicken on a baking sheet and refrigerate for 30 minutes.
Heat vegetable oil in a dutch oven or deep skillet to 350 degrees F.
Beat buttermilk, eggs, honey, and truffle salt in a shallow pan.
Dip floured chicken breasts into the buttermilk mixture, then gently place them into the hot oil.