Trim the fat from the chicken breasts and cut each into 1-inch chunks.
In a medium bowl, combine flour, salt, black pepper, paprika, and cayenne pepper.
In a separate bowl, whisk together the milk and egg.
Dip each chicken piece into the milk mixture, allowing any excess to drip off.
Coat the chicken pieces in the flour mixture, ensuring they are evenly covered.
Heat the vegetable oil in a deep fryer or large pot to 375°F.
Fry the chicken pieces in batches for about 5 minutes until golden brown and cooked through. Drain on paper towels.
In a microwave-safe bowl, combine hot sauce, butter, and garlic powder. Heat in microwave for about 20 seconds and stir well.
Toss the fried chicken pieces in the sauce until they are well-coated.